Exploring the molecular basis of labile heme as a prothrombotic modulator in hemolytic disorders

(GTH Early Career Research Grant

The aim of this project is to provide knowledge about the molecular basis of heme-driven effects on factors of the blood coagulation system in the context of prothrombotic complications in patients suffering from hemolytic disorders.

Publications

Hopp, M.-T.*, Ugurlar, D., Pezeshkpoor, B., Biswas, A., Ramoji, A., Neugebauer, U., Oldenburg, J., Imhof, D.* (2024) In-depth structure-function profiling of the complex formation between coagulation factor VIII and heme. Thromb. Res. 237: 184-195.

Fundings & Partners


Participating organizational units
Bioorganic Chemistry Groupuni-koblenz.de/en/mathematics-...
Funded by
Society for Thrombosis and Hemostasis Research e.V.gth-online.org

Contact

Jun.-Prof. Dr. Marie-T. Hopp

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B.Sc. Afia Riaz

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B.Sc. Bhuvana G. K. Bhatt

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